Calm

Physiological Sigh (Cyclic Sighing)

Two breaths in through the nose, one long breath out. Calmer in one or two breaths.

Also called: Cyclic sighing, Double inhale, Double inhale, long exhale, Huberman breathing technique

The physiological sigh is a breathing pattern of two inhales through the nose, the second a short top-up, followed by one long exhale through the mouth. It copies the sigh your body already takes on its own every few minutes[2].

Use one or two sighs when stress hits, or repeat it for 5 minutes as a daily practice. The long exhale drops your shoulders and settles you, and you'll feel calmer after one or two breaths.

Pattern
Inhale, a short second inhale, then a long exhale (Spoon: 3 s, 1 s, 7 s)
Session
1 or 2 sighs in the moment; 5 minutes as a daily practice
Good for
Sudden stress, and a 5-minute daily mood practice
Level
Beginner
Origin
Popularized by Stanford neuroscientist Andrew Huberman; tested at Stanford as cyclic sighing
Needs
iPhone or Apple Watch

Try it now

Breathe in 3 s · Top up 1 s · Long sigh out 7 s

Follow the circle for a few rounds. In Spoon you can do it from your wrist and see your heart rate respond.

How to do it

  1. Sit, stand or lie down. Eyes open is fine, so you can do it in the middle of a task.
  2. Breathe in through your nose: a comfortable, full breath, not a gasp.
  3. Without breathing out, sip in a second, shorter breath through your nose to top up your lungs.
  4. Breathe out slowly through your mouth until your lungs feel empty. Make the exhale longer than both inhales together.
  5. In the moment, one or two sighs are enough. As a daily practice, repeat at an easy pace for 5 minutes.
  6. Finish on an exhale and let your breathing return to its own rhythm.

Benefits

  • Calmer in one or two breaths

    The long exhale is the part that settles you. One or two deep sighs already take the edge off[5].

  • A better mood with daily practice

    In a month-long Stanford trial, 5 minutes of cyclic sighing a day lifted positive mood more than mindfulness meditation did[1].

  • Slower breathing at rest

    The same trial found the largest drop in resting breathing rate in the cyclic sighing group[1].

  • Use it anywhere, eyes open

    No posture, no equipment and no need to stop what you're doing. It fits at your desk, in a waiting room or before a call.

What the research says

The deliberate practice was tested in a 2023 Stanford trial. 108 adults were randomly assigned to 5 minutes a day, for 28 days, of cyclic sighing, box breathing, cyclic hyperventilation with breath holds, or mindfulness meditation[1]. Cyclic sighing raised daily positive mood significantly more than meditation, and the benefit grew over the month[1][5]. It also gave the largest drop in resting respiratory rate[1]. Anxiety and negative mood fell in all four groups, with no significant difference between them, and heart rate and heart rate variability did not change significantly[1].

The trial measured a month of daily practice, not how quickly a single sigh calms you in the moment[1]. In Stanford's write-up of the trial, David Spiegel suggests about 5 minutes of sighing, and the article notes that you may feel calmer after just one or two[5].

The sigh reflex itself is mapped in mice. Li and colleagues found small groups of brainstem neurons that release the peptides neuromedin B and gastrin-releasing peptide onto the preBötzinger complex, the breathing rhythm generator; blocking both receptors abolished sighing[2]. Sighs happen on their own every few minutes and reinflate the lungs' tiny air sacs, the alveoli[2].

In people, Vlemincx and colleagues propose that a sigh resets breathing that has turned irregular, and that this reset brings relief[3]. In one of their lab studies, an instructed deep breath raised people's sense of relief, and a spontaneous sigh lowered forehead-muscle tension in people with high anxiety sensitivity[4].

Tips

  • Don't breathe out between the two inhales. Stack the second sip right on top of the first.
  • Keep the second inhale small: a comfortable first breath, then just enough to top up.
  • Slow the exhale until it clearly outlasts both inhales together.
  • Keep the pace easy. This is not fast breathing; if you feel lightheaded, slow down.
  • Nose blocked? Do the whole pattern through your mouth.

Safety

  • Stop and breathe normally if you feel lightheaded, especially after many sighs in a row. Slow the pace instead of pushing on.
  • Don't practice it while driving or in water.
  • If you're pregnant or have a heart, lung or serious mental health condition, check with your doctor before making it a daily practice.
  • If focusing on your breath makes you more anxious, stop and try something else.

Physiological Sigh in Spoon

Spoon guides the Physiological Sigh on iPhone and Apple Watch in two modes. Continuous runs a timed session, 5 minutes by default, the daily dose the Stanford trial tested. Quick Calm gives you 1 or 2 guided sighs for the moment stress hits.

The timing is set for you: a 3-second inhale, a 1-second top-up and a 7-second exhale. Follow a breathing bubble or a wave on iPhone, or the breathing circle on your Watch, with breath sounds and wrist taps marking the phases. Turn on the voice (Guided Session: Voice) and your iPhone says "Inhale", "Top up" and "Exhale".

  • Two modes: Continuous (1, 3, 5 or 10 minutes) and Quick Calm (1 or 2 sighs).
  • Fixed timing of 3 s in, 1 s top-up and 7 s out: about 5 sighs a minute.
  • Breath sounds and wrist taps, both on by default and easy to switch off.
  • Optional voice on iPhone, in English or Spanish.
  • With an Apple Watch: live heart rate, then your breath and heart rate on one chart.
  • Save it, or add it to a playlist.

Free public beta for iPhone and Apple Watch.

Questions

How many physiological sighs should you do?

One or two take the edge off a stressful moment. As a daily practice, repeat it for about 5 minutes, the dose the Stanford trial tested for 28 days. More is not better: if you feel lightheaded, stop and breathe normally.

Physiological sigh vs box breathing: which is better?

Both calm you down. In a month-long Stanford trial, cyclic sighing lifted mood the most and slowed resting breathing the most, while box breathing did not differ significantly from meditation on those measures. The sigh has no holds, so it's easy to use mid-task. Box breathing gives you a steady count when you want calm with focus.

Is the physiological sigh the fastest way to calm down?

That claim goes beyond the research. The Stanford trial tested 5 minutes a day for a month, not speed in a single moment, and found that cyclic sighing lifted mood and slowed resting breathing more than mindfulness meditation. In the moment, one or two sighs calm you quickly, and you can check that on your own body.

Should you breathe through your nose or your mouth?

The classic form is both inhales through the nose and the exhale through the mouth. In the Stanford trial, breathing out through the nose was also fine. If your nose is blocked, do the whole pattern through your mouth.

Is the physiological sigh the same as cyclic sighing?

Same breath, different dose. The physiological sigh usually means one or a few sighs in the moment. Cyclic sighing is the name the Stanford team gave to repeating it for 5 minutes as a daily practice.

What does a physiological sigh feel like?

The second inhale feels like a small extra sip that fills your lungs to the top. Then the long exhale empties your lungs and your shoulders drop. You'll feel calmer after one or two.

Sources

  1. Balban MY, et al. Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Reports Medicine, 2023. pmc.ncbi.nlm.nih.gov
  2. Li P, et al. The peptidergic control circuit for sighing. Nature, 2016. doi.org
  3. Vlemincx E, et al. Respiratory variability and sighing: a psychophysiological reset model. Biological Psychology, 2013. doi.org
  4. Vlemincx E, et al. A sigh of relief or a sigh to relieve: The psychological and physiological relief effect of deep breaths. Physiology & Behavior, 2016. doi.org
  5. Leggett H. Cyclic sighing can help breathe away anxiety. Stanford Medicine News Center, 2023. med.stanford.edu

Updated October 2026. This page is for education, not medical advice. If you have a heart, lung or blood pressure condition, epilepsy, or you are pregnant, ask your doctor before you start a breathing practice with holds or fast breathing.